Progressive Multifocal leucoencephalopathy (PML)-MRI

This is a case of known case of AIDS (46yr old male) on Antiretroviral therapy, who developed right sided weakness and memory loss. MRI reveals T2/FLAIR left parietal hyperintensity with diffusion restriction on DWI. There is involvement of splenium of corpus callosum. No post gadolinium enhancement was seen. There was subtle mass effect. Diagnosis of Progressive Multifocal leucoencephalopathy was made (PML). Relative lack of mass effect, non enhancing nature and classical location are points in favor of the diagnosis.

Dr.Sumer K Sethi, MD

Sr Consultant Radiologist ,VIMHANS and CEO-Teleradiology Providers

Editor-in-chief, The Internet Journal of Radiology

Director, DAMS (Delhi Academy of Medical Sciences)