Thursday, December 30, 2010

PET Isotopes produced without cyclotron



Advantage of PET is the use of the positron emitting biologic radiotracers, e.g., 11C, 13N, 15O ,  and most important 18F (Half life = 110 min) that mimic natural substrate. However, due to relatively short half-lives, they are unable to be transported to sites at great distances from the production facility.

(Generator nuclides)

44Sc --- Bone disease
 68Ga  --- Blood–brain barrier; tumor localization
72As-- Toxicological study
82Rb Myocardial perfusion
118Sb First pass angiography
128Cs Myocardial perfusion

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