Tuesday, October 7, 2008

Tubercular Meningitis with Trapped Ventricle-MRI




This is a case of tubercular meningitis with choroid plexitis and trapped temporal horn of lateral ventricle seen on MRI. Note the abnormal enhancment of choroid plexus.
Dr.Sumer K Sethi, MD
Sr Consultant Radiologist ,VIMHANS and CEO-Teleradiology Providers

Colloid Cyst-MRI




The term colloid cyst refers to only neuroepithelial cysts that arise in the anterosuperior third ventricle, near the foramina of Monro. The cysts are lined by a single layer of epithelial cells and are typically filled with a thick, viscous mucus that has an array of ingredients, including blood products, macrophages, cholesterol crystals, and numerous metallic ions, such as copper, iron, magnesium, aluminum, and phosphorus. This is a 18 year old female who presented with complaints of headache. Note the cyst is hyperintense on T1 weighted image.

Monday, October 6, 2008

Supraspinatus Calcific Tendonitis-CT


"Painter described calcification in the shoulder in 1907. Codman established that the calcification was within the tendons of the rotator cuff. Calcifying tendinitis of the shoulder is characterized by the presence of macroscopic deposits of hydroxyapatite (a crystalline calcium phosphate) in any tendon of the rotator cuffEven supraspinatus tendons that are macroscopically normal contain minute amounts of calcium deposits. Degenerative tendons that have ruptured contain more calcium deposits, but it is not always in the form of calcium phosphate. The increase in calcium deposits is due to degenerative calcification.In contrast, the calcium in tendons with radiographically visible calcification is in the form of crystalline hydroxyapatite. Calcifying tendinitis is a different condition from that of degenerative tendons in which there is a small increase in calcium content. genral asymptomatic population in 30 to 50 yrs display calccificatin in about 3 to 20%The supraspinatus tendon is affected most often. Calcification is observed with decreasing frequency in the infraspinatus, teres minor, and subscapularis tendons. More than one tendon may be involved. Women are affected slightly more frequently than are men (housewives and clerical workers account for most cases), and the right shoulder is affected slightly more often than the left is. Both shoulders can have or develop calcific deposits in 13-47% of subjects, and the calcific deposit usually is described as being approximately 1-2 cm proximal to the tendon insertion on the greater tuberosity. Computed tomography (CT) scanning may be used to accurately localize the calcific deposit."

Case by Dr MGK Murthy, Sr Consultant Radiologist
&
Dr.Sumer K Sethi, MD
Sr Consultant Radiologist ,VIMHANS and CEO-Teleradiology Providers

Saturday, October 4, 2008

A Midnight Walk in Downtown Manila

Plaza Lacson at 11 P.M.

As was my usual custom, I went to downtown Manila last Friday to attend the traditional Quiapo evening mass. I arrived late in the evening, but was just in time for the last Eucharist service. I usually just sit at the far end of the pew at the back of the church.

Upon entrance I dipped my hand to the holy water being held by one of the ancient stone angels located near the entrance, and after that made a sign of the cross. I knelt for a while and try to contemplate on the homily. After receiving communion, I headed to the room of The Holy Sepulchre to say the rosary. A few people were already there and since there were no chairs or benches, some people were kneeling, and some in indian-sit position.

Everyone must remove their shoes prior to entering the air-conditioned room. So that other people will not run away with your shoes, a number tag was given that will serve as claim stub. No wonder the floor was very clean and shiny. In the entrance was a sign that reads: "Bawal Tumambay sa Loob". This was a warning to people not to use the Holy Sepulchre room to relax and cool themselves. Apparently, some people were caught in the past sleeping inside the air-conditioned room.

But none do so now. Everyone was saying their prayers, most were probably asking for blessings or personal favors to the Holy Altar. After saying my rosary, I bowed to the altar and proceeded outside to walk awhile.

Outside the Church, the sidewalk vendors offered me several merchandise like candles, rosaries, cigarettes, candies, toys, flowers, and a different assortments of what you'd usually find for sale in front of the church every Sunday. I did not buy anything except a small sampaguita necklace I will hang in the altar of my home.

There were also some beggars, street children and disabled people at the church's entrance. I bought a plastic bag from one of the boys and gave some coins to the beggars and disabled people. I always pity them, and wish I were as rich as Lucio Tan so I can give them food everyday, or better, livelihood. But I was only a middle-class person also trying to survive the economic crisis in our poor republic.

As my usual habit, I tried to photograph some night sceneries with my camera, while walking the little familiar streets of downtown Quiapo and Avenida Rizal. It was already past 11 in the evening, and I began to notice that many of the stores were already closing down. Some vendors were already packing their merchandise, and many were already on their way back home after the usual hectic day.

Downtown Manila in late evening is an interesting sight to behold. The cool breeze of October air and the lonely glow of the incandescent street lamps added to the nostalgic ambiance of the general atmosphere.

Like Cubao, downtown Manila assumes a different personality after the last daylights disappeared from the sky. And here I have recorded the familiar sights of Manila....by night...It was not all lovely, but I guess you will agree that these images make Manila one of the most interesting cities in the Far East.

So, let me invite you to a romantic walk with me in the lovely streets of downtown Manila in a fine cool late evening.


It's closing time


Once in a while, a few jeepneys still ply downtown to bring night

workers to their respective homes.


Corner of Avenida Rizal and Recto.11:30 pm


Fishballs for sale for the night workers


Preparing tomorrow's merchandise



The jeepney is an obiquitous presence in the downtown, even at very late in the evening.



Plaza Miranda, Quiapo, right after the last evening mass


The sidewalk vendors trying to sell their wares near the front of the Church


After a hard day's work, a play of cards is a welcome relaxation.


Street kids of Avenida. Tired of begging, and ready to sleep.


Shopping for the pirated dvds.



Near the famous Quinta Market


Avenida sidewalk. Or known as the bangketa.


Going home


The kalesa, once the proud king of downtown, is just now considered a curiosity ride in Manila.


Waiting for the jeepneys.


The cigarette and candy man of Carriedo


Ambulant cigarette vendor


A street scenery in Carriedo





The pirated cds and dvds are very popular in Manila.



In front of the newly-renovated Cinerama, an old stomping ground during my college days.



The Dama players of Avenida. Even Kasparov will be hard-pressed to beat them in Dama.


In Manila as in Cubao, sleep is wherever you can find it.


A tender toddler plays in the bangketa of Avenida, while pedestrians walk past her from all directions.


The pedicab man must work even late at night to support his family.



While the other pedicab drivers patiently wait for their midnight riders


But this man was too tired to wait. His faithful pedicab serves as a makeshift bed to doze off for a while.


The old Dilson cinema in Azcarraga (now C.M. Recto Avenue)


Mother and child in an almost deserted Avenida Rizal. 12 am.


So long!

Thursday, October 2, 2008

Don't Vote

Ok, so this has a lot of celebrities in it, and it's not super funny, but it has a good message, so watch it. Just wait until you're about a minute and twenty seconds in, and then it will BLOW YOUR MIND!!!!!


Congenital cystic intracranial neoplasm








Findings

Figure 1: Prenatal ultrasound demonstrates a 4 x 5 cm intracranial lesion in the region of the right middle cranial fossa, with multiple cystic and heterogeneously echoic soft tissue areas.
Figure 2, Figure 3, and Figure 4: MR images at 32 weeks 3 days gestation. Coronal (Figure 2) and sagittal (Figure 3) single shot T2 weighted (SShT2) images and axial (Figure 4) fast field echo (FFE) image of the fetal head show a large cystic lesion with multiple internal cysts and soft tissue components in its inferior aspect in the region of the right temporal lobe. (SShT2: repetition time 15000 milliseconds, echo time 120 milliseconds, flip angle 90, number of excitations 2)
(FFE: repetition time 5.3 milliseconds, echo time 2.6 milliseconds, flip angle 60, number of excitations 2)
Figure 5: Newborn non-enhanced axial CT image shows a multicystic heterogeneous lesion within the right temporal lobe containing calcification.

Differential diagnosis of complex cystic neonatal intracranial masses:
- Teratoma
- Astrocytoma
- Hemangioma
- Cystic ependymoma


Diagnosis: Congenital cystic intracranial neoplasm


Congenital brain tumors represent only 0.5-1.9% of all pediatric brain tumors, but of these, intracranial teratomas are the most common tumor in the neonatal period. They are congenital neoplasms derived from all three embryonic layers and contain ectodermal, endodermal, and mesodermal elements and are thought to arise from embryonic cells that fail to differentiate or migrate. They originate in the 3rd to 4th weeks of fetal development, have mixed density, and are most commonly found in the pineal and suprasellar regions.

Extragonadal teratomas are thought to arise from misplaced, pluripotential, primordial germ cells. According to one theory, some of the embryonic germ cells fail to migrate normally and these ectopic germ cells become embedded in or near midline structures. The ectopic cells retain their pluripotent capabilities and may develop into teratomas or other types of germ cell neoplasms.

Intracranial teratomas can be divided into two categories with those occurring in the cerebral hemispheres and those occurring in the pineal region. Those appearing in the cerebral hemispheres are typically large and are usually discovered in the newborn period. Those in the pineal region manifest symptoms later on and are usually smaller. Intracranial teratomas are extremely rare tumors and are usually diagnosed after birth, but they have been discovered prenatally via ultrasound.

Of the intracranial prenatal neoplasms, teratomas and primitive neuroectodermal tumors (PNETs) are the most common. If a heterogeneous prenatal cystic mass is identified, a congenital cystic teratoma should be at the top of the differential diagnosis. Imaging features of teratomas show both lipid and calcification. Characteristics that help to differentiate teratomas from PNETs are the presence of lipid and the lack of blood breakdown products, which are often seen in PNETs.

When ultrasound demonstrates a brain lesion, prenatal MRI can be used to define the characteristics and extent of the tumor while also delineating the relationship of the lesion with adjacent structures. MRI is not only useful for correct diagnosis, but it also may obviate the need for immediate postnatal imaging of the newborn and findings can determine potential resectability and guide surgical planning. In this case, the prenatal MR imaging was used in prenatal diagnosis and aided in pregnancy and surgical management. While it has been shown that a fetus with an arachnoid cyst can safely undergo normal spontaneous vaginal delivery, the diagnosis of teratoma in this patient altered both the method and timing of delivery in this patient.

Wednesday, October 1, 2008

Lupus cerebritis











Findings

Diffuse, predominantly white matter T2/FLAIR hyperintense signal spares only the anterior temporal lobes. Focal lesions with hypointense T1 signal, low T2 signal, are heterogeneously hypointense on gradient echo, do not show restricted diffusion, and rim enhance. Ventricles, sulci, and cisterns remain normally configured and are of normal size for patient's age. No midline shift. Normal flow-voids in the major intracranial arteries.

Differential diagnosis:
- Lupus cerebritis
- Atypical infection
- Severe progressive PRES (posterior reversible encephalopathy syndrome) with high-dose steroids

Commentary: Initial study (not showed) has findings typical of lupus encephalopathy. The focal lesions in the second study are almost certainly hemorrhage. Given the rapid progression of these abnormalities, patient's history of lupus, and the development of multiple hemorrhagic foci, lupus cerebritis is most likely, with less likely differential diagnoses including severe progressive PRES with high dose steroids or atypical infection.


Diagnosis: Lupus cerebritis (presumed)


Key points

One acute subcategory of neuropsychiatric systemic lupus erythematosus (NPSLE).

Clinical
- Neurologic disorder which can present with any neurologic sign or symptom.
Focal: Seizure
Diffuse: Psychosis

Laboratory
- May be associated with high anti-ribosomal P autoantibody.
- Role of imaging
Assessment of acute focal (stroke-like) neurologic deficits.
CNS vasculitis.
Reported in up to 7% of SLE patients.


Radiology

High T2 signal in white matter.
- Sometimes in vascular distribution.
- Involves cortical and subcortical areas.
- Particularly occipital region.
- Relative sparing of periventricular white matter relative to MS.

Atrophy: Commonly found, secondary to
- Encephalopathy
- Steroid use

- Lesions may evolve in 7-10 day course
- Also possible
Hemorrhage
Subarachnoid
Intraparenchymal
Infarct
Aneurysms also reported