An article by Setsuko Kawase et al "Relationship between CT densitometry with a slice thickness of 0.5 mm and audiometry in otosclerosis" in European Radiology June 2006 authors determined The appropriate cutoff Hounsfield unit (HU) value for the diagnosis of otosclerosis and investigated the correlation between the bone conduction threshold and the findings of computed tomography (CT) densitometry. Based on receiver operating characteristic (ROC) analysis, the cutoff HU value in area anterior to the oval window (A-OW) was determined to be 2,187.3 HU. A statistically significant correlation was found between the density of the area A-OW and the hearing level at 500 and 1,000 Hz, and between the density of the area around the cochlea and the hearing level at most frequencies. These results suggest the semi-automated diagnosis of otosclerosis may be possible.
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