Saturday, March 25, 2006

Gaolinium-Neurotoxicity??

In an article by Maramattom BV et al, Gadolinium encephalopathy in a patient with renal failure in Neurology 2005 Apr 12;64(7):1276-8 authors discuss a case of gadolinium encephalopathy.
"Gadolinium chelates are extensively used in MRI studies. Neurotoxicity due to gadolinium chelates is minimal and uncommon. A 57-year-old woman in renal failure developed a subacute encephalopathy after inadvertent repetitive gadolinium contrast administration. An unusual MRI appearance with CSF hyperintensity due to gadolinium diffusion into the CSF is also shown"

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