Tuesday, April 24, 2007

Glioblastoma multiforme







Findings

Multiple enhancing masses with surrounding vasogenic edema and mass effect in the left cerebral hemisphere. There is associated sulcal effacement, gyral expansion/thickening, and mass effect with approximately 9-mm midline shift toward the right.


Diagnosis: Glioblastoma multiforme


Glioblastoma multiforme (GBM) is unfortunately both the most common and the most malignant of the glial tumors.
Of approximately 17,000 primary brain tumors diagnosed in the U.S. every year, 60% are glial tumors. Males have a slight predominance: 1.5 to 1.

The World Health Organization classification:
- Grade II: Low-grade diffuse astrocytoma
- Grade III: Anaplastic astrocytoma
- Grade IV: Glioblastoma multiforme

GBMs often arise in the subcortical white matter of the cerebral hemispheres. 31% arise in the temporal lobes. 24% arise in the parietal lobes. 23% arise in the frontal lobes and 16% arise in the occipital lobes. Sites such as the brain stem, cerebellum and spinal cord are much less common.
Classically, GBM has a thick, irregular enhancing ring of neoplastic tissue which surrounds a necrotic core.

The differential diagnosis for GBM includes:
- Abscess: Ring enhancement is usually thinner than GBM
- Metastases: Usually multiple lesions at gray-white junction
- Anaplastic astrocytoma: Usually nonenhancing white-matter mass. Enhancement may suggest degeneration to GBM
- Primary CNS lymphoma: Periventricular enhancing mass which often crosses the corpus callosum
- Tumefactive demyelination: Usually incomplete "horseshoe" enhancement which is open toward the cortex

1 comment:

  1. I have long felt a special connection with herbal medicine. First, it's natural, Charlie attended the same small college in Southern California - Claremont Men's College - although he dropped out of school to enroll in the Julliard School of Performing Arts in New York. York. Had he been to Claremont, he would have been senior the year I started there; I often thought that was the reason he was gone when he discovered that I had herpes. So, my life was lonely, all day, I could not stand the pain of the outbreak, and then Tasha introduced me to Dr. Itua who uses her herbal medicines to cure her two weeks of consumption. I place an order for him and he hands it to my post office, then I pick it up and use it for two weeks. All my wound is completely healed no more epidemic. I tell you honestly that this man is a great man, I trust him Herbal medicine so much that I share this to show my gratitude and also to let sick people know that there is hope with Dr. Itua. Herbal Center.Dr Itua Contact Email.drituaherbalcenter@gmail.com/Whatsapp ... +2348149277967
    He cures.
    Herpes,
    Prostate
    Breast Cancer
    Brain Cancer
    CEREBRAL VASCULAR ACCIDENT.
    ,Endomertil Cancer, cerebrovascular diseases
    Hepatitis,Glaucoma., Cataracts,Macular degeneration,Cardiovascular disease,Lung disease.Enlarged prostate,Osteoporosis.Alzheimer's disease,
    Dementia.Tach Disease,Shingles,
    Lung Cancer, Leukemia Lymphoma Cancer,
    Lung Mesothelioma Asbestos,
    Ovarian Cervical Uterine Cancer,
    Skin Cancer, Brain Tumor,
    H.P.V TYPE 1 TYPE 2 TYPE 3 AND TYPE 4. TYPE 5.
    HIV,Arthritis,Amyotrophic Lateral Scoliosis,Fibromyalgia,Fluoroquinolone Toxicity
    Cervical Cancer
    Colo-rectal Cancer
    Blood Cancer
    SYPHILIS.
    Diabetes
    Liver / Inflammatory kidney
    Epilepsy

    ReplyDelete