Wednesday, September 12, 2007

Gliomatosis Cerebri-MRI & MRS



Gliomatosis cerebri (infiltrative diffuse astrocytosis) is a rare primary brain tumor. It is commonly characterized by diffuse infiltration of the brain with neoplastic glial cells that affect various areas of the cerebral lobes. Before the advent of MRI, diagnosis was generally not established until autopsy. Typically, gliomatosis cerebri appears as a diffuse, poorly circumscribed, infiltrating non-enhancing lesion that is hyperintense on T2-weighted images and expands the cerebral white matter. The prognosis for gliomatosis cerebri is generally poor, with a median survival time of only 12 months.

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