Monday, September 4, 2006

Imaging finding in GIST

Reference-Gastrointestinal stromal tumors: CT and MRI findings. in Eur Radiol 2005 Jul;15(7):1407-14. Epub 2005 Mar 11 By Sandrasegaran K

"Primary tumors were typically exophytic, larger than 5 cm, and inhomogeneously enhancing.Central necrosis of all tumors and aneurysmal dilation of enteric tumors (33%) were less common. Metastases were most commonly to mesentery or liver. Less common findings were ascites and omental caking . Liver metastases were hypervascular in 92% of patients and rapidly became cystic following therapy with imatinib mesylate. Lung metastases, bowel obstruction, vascular invasion, and significant lymphadenopathy were not seen in any patient. GISTs have some specific CT findings which could help differentiate them from other gastrointestinal tumors. Liver metastases became cystic following therapy, mimicking simple cysts. MRI was better than single-phase CT for assessing liver metastases, while CT was more sensitive for mesenteric metastases."

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